Almost any load bearing wall can be safely removed. The key is to use appropriately sized material to redirect the load previously supported by the wall that is going away. This is where a professional is going to earn his/her money. There are a variety of options (LVL or Microlam, Gluelam or power beam, girder truss) that can be used to correctly handle this part of the project. Engineers and structural framing professionals have tools that allow them to input the specifics of each situation into an engineering program, correctly calculate the load and then recommend the correct product to cross the new span.
Load Bearing Wall Pros use Anthony Forest Products for these products for wall removal in the DFW metroplex. Click the image below to see what products the pros are using.